JUNE 2011
Report Authors
James Andersen
Danielle L. Drayton, Ph.D.
Introduction:
The hospital anti-infectives market is a high-value segment of the overall antibacterial market, due, in part, to a variety of unmet needs, the increasing prevalence of drug-resistant pathogens, and the routine use of premium-priced agents. In this report, we use patient-level audit data to review the overall landscape of the hospital anti-infectives market, with particular emphasis on the four of the most common bacterial infections treated in the hospital setting—skin and skin structure infections, urinary tract infections, bloodstream infections, and hospital-acquired pneumonia. Moreover, this report analyzes the use of current antibiotic brands and other highly prescribed generic treatments to provide insight into how current therapies are used and how their use has changed over the last five years. With numerous antibiotics spanning a diverse set of classes and the impending patent expiries of key antibiotic brands, the hospital anti-infectives market stands to become increasingly competitive
, necessitating a granular understanding of various market segments and associated commercial opportunities. To that end, this report also combines insight from U.S. infectious disease specialists with patient-level audit data to identify and evaluate market opportunities in hospital anti-infectives and assess the potential use and positioning of new and emerging therapies.
Scope:
In this study, we use clinical patient-level audit data from the Arlington Medical Resources, Inc. (AMR) Hospital Antibiotic Market Guide to examine the current landscape of patients, pathogens, product usage, and prescribers in the hospital anti-infectives market, including the following:
- Analysis of key product usage by treatment intent, line of therapy, diagnosis (including diagnosis values), and pathogen.Patient population analysis and segmentation by diagnosis, community- versus hospital-acquired infection, age, co-morbidities (including renal and hepatic impairment), risk factors, and hospitalization outcomes.
- Behavior of the top specialties that prescribe antibiotics in the hospital setting.
- Insight from 100 surveyed U.S. infectious disease specialists on unmet needs in the hospital anti-infectives market, together with these specialists' receptivity to recently launched and emerging therapies.